Run

Max iterations

10

Mutation rate 0.2 LLM confidence threshold 0.6 Plateau window

10

LLM

Use LLM agents Model

gpt-4o-mini gpt-4o claude-3-5-sonnet

gpt-4o-mini

Protein folding

Modal fold (remote) Folding Engine

esmfold omegafold alphafold dummy

esmfold

Rosetta engine

Use Rosetta Rosetta relax Relax cycles

0 1 2 3 4 5

0